Premature Mortality from Cardiovascular Disease in the Americas - Will the Goal of a Decline of "25% by 2025" be Met?
Premature Mortality from Cardiovascular Disease in the Americas - Will the Goal of a Decline of "25% by 2025" be Met?
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DOI：
10.1371/journal.pone.0141685
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发表时间：
2015-10-29
期刊：
影响因子：
3.7
通讯作者：
Cooper, Richard S.
中科院分区：
文献类型：
--
作者：
Ordunez, Pedro;Prieto-Lara, Elisa;Cooper, Richard S.
背景心血管疾病 (CVD) 是美洲每年 160 万人死亡的根本原因，占总死亡率的 30%，占非传染性死亡疾病 (NCD) 死亡人数的 38%。 2011 年预防和控制非传染性疾病大会高级别会议确定了将四种主要非传染性疾病造成的过早死亡率降低 25% 的目标。虽然过去十年美洲的 CVD 死亡率总体有所下降，但同期 CVD 过早死亡率的趋势尚未描述，特别是在拉丁美洲和加勒比国家。方法这是一项基于人口的趋势系列研究，基于总共 6,133,666 例死亡，旨在描述 CVD 过早死亡的趋势和特征，并估计 2000-2010 年期间美洲因 CVD 过早死亡的趋势和特征。 2000年至2010年期间，美洲CVD死亡率下降了21%，过去5年平均年变化率为-2.5%，死亡率在统计上显着下降。缺血性疾病死亡率男性下降了 25%-24%，女性下降了 26%。男性脑血管疾病下降27%-26%，女性下降28%。圭亚那、特立尼达和多巴哥、多米尼加共和国、巴哈马和巴西的 CVD 过早死亡率为每 10 万人口 200 人以上，而该区域的平均死亡率为 132.7 人。美国和加拿大将在 2025 年前实现减少 25% 的目标。墨西哥、哥斯达黎加、委内瑞拉、多米尼加共和国、巴拿马、圭亚那和萨尔瓦多没有显着降低男性过早死亡率，圭亚那、多米尼加共和国和巴拿马也没有实现所需的年度女性过早死亡率降低目标。结论过去十年在美洲观察到的因心血管疾病导致的过早死亡率趋势表明，如果这些趋势持续下去，整个区域及其大多数国家将能够达到甚至在 2025 年之前就将过早死亡率相对降低 25% 的目标。
BackgroundCardiovascular diseases (CVD) are the underlying cause 1.6 million deaths per year in the Americas, accounting for 30% of total mortality and 38% of by non-communicable deaths diseases (NCDs). A 25% reduction in premature mortality due four main NCDs was targeted by the 2011 High-level Meeting of the General Assembly on the Prevention and Control of NCDs. While overall CVD mortality fell in the Americas during the past decade, trends in premature CVD mortality during the same period have not been described, particularly in the countries of Latin America and the Caribbean.MethodsThis is a population-based trend-series study based on a total of 6,133,666 deaths to describe the trends and characteristics of premature mortality due to CVD and to estimates of the average annual percentage of change during the period 2000-2010 in the Americas.FindingsPremature mortality due to CVD in the Americas fell by 21% in the period 2000-2010 with a -2.5% average annual rate of change in the last 5 year-a statistically significant reduction of mortality-. Mortality from ischemic diseases, declined by 25% -24% among men and 26% among women. Cerebrovascular diseases declined by 27% -26% among men and 28% among women. Guyana, Trinidad and Tobago, the Dominican Republic, Bahamas, and Brazil had CVD premature mortality rates over 200 per 100,000 population, while the average for the Region was 132.7. US and Canada will meet the 25% reduction target before 2025. Mexico, Costa Rica, Venezuela, Dominican Republic, Panama, Guyana, and El Salvador did not significantly reduce premature mortality among men and Guyana, the Dominican Republic, and Panama did not achieve the required annual reduction in women.ConclusionsTrends in premature mortality due to CVD observed in last decade in the Americas would indicate that if these trends continue, the Region as a whole and a majority of its countries will be able to reach the goal of a 25% relative reduction in premature mortality even before 2025.