Hypocretin/orexin regulation of dopamine signaling: implications for reward and reinforcement mechanisms.
Hypocretin/orexin regulation of dopamine signaling: implications for reward and reinforcement mechanisms.
复制标题
多巴胺信号传导的低载染/甲氧素调节：对奖励和增强机制的影响。
DOI：
10.3389/fnbeh.2012.00054
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发表时间：
2012
影响因子：
3
通讯作者：
España RA
中科院分区：
文献类型：
--
作者：
Calipari ES;España RA
The hypocretins/orexins are comprised of two neuroexcitatory peptides that are synthesized exclusively within a circumscribed region of the lateral hypothalamus. These peptides project widely throughout the brain and interact with a variety of regions involved in the regulation of arousal-related processes including those associated with motivated behavior. The current review focuses on emerging evidence indicating that the hypocretins influence reward and reinforcement processing via actions on the mesolimbic dopamine system. We discuss contemporary perspectives of hypocretin regulation of mesolimbic dopamine signaling in both drug free and drug states, as well as hypocretin regulation of behavioral responses to drugs of abuse, particularly as it relates to cocaine.
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影响因子：
16.2
作者：
Borgland, SL;Taha, SA;Bonci, A
通讯作者：
Bonci, A
DOI：
10.1073/pnas.0507480102
发表时间：
2005-12-27
影响因子：
11.1
作者：
Boutrel, B;Kenny, PJ;de Lecea, L
通讯作者：
de Lecea, L
影响因子：
3.4
作者：
Borgland, S. L.;Storm, E.;Bonci, A.
通讯作者：
Bonci, A.
影响因子：
3.3
作者：
España, RA;Baldo, BA;Berridge, CW
通讯作者：
Berridge, CW
DOI：
10.1124/jpet.109.152009
发表时间：
2009-07-01
影响因子：
3.5
作者：
Dugovic, Christine;Shelton, Jonathan E.;Lovenberg, Timothy W.
通讯作者：
Lovenberg, Timothy W.