DEVELOPMENTAL RELATIONSHIPS BETWEEN VITELLINE AND INTRA-EMBRYONIC HEMATOPOIESIS STUDIED IN AVIAN YOLK-SAC CHIMAERAS
DEVELOPMENTAL RELATIONSHIPS BETWEEN VITELLINE AND INTRA-EMBRYONIC HEMATOPOIESIS STUDIED IN AVIAN YOLK-SAC CHIMAERAS
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DOI：
10.1016/0045-6039(78)90012-x
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发表时间：
1978-01-01
期刊：
影响因子：
--
通讯作者：
DIETERLENLIEVRE, F
中科院分区：
文献类型：
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作者：
MARTIN, C;BEAUPAIN, D;DIETERLENLIEVRE, F
应用鹌鹑-鸡标记技术，对149只由鹌鹑胚胎和鸡卵黄囊组成的嵌合体的造血器官进行了细胞示踪。证实了先前用该系统证明的胚胎内干细胞中继卵黄囊干细胞的存在。胸腺、腔上囊和骨髓中的胚胎干细胞优先聚集。鸡卵黄囊干细胞在脾脏中的定植时间为11-12天。从第7天开始，卵黄囊接受从胚胎迁移的鹌鹑干细胞。
Using the quail-chick marker technique, cells were traced in the hemopoietic organs of 149 developing chimaeras composed of a quail embryo with a chick yolk sac. The existence of intraembryonic stem cell relaying yolk sac stem cells, previously demonstrated with this system was confirmed. Thymus, bursa of Fabricius and bone marrow were preferentially populated by intraembryonic stem cells. The spleen showed a transitory plase of colonization by chick yolk sac stem cells at 11-12 days of incubation. From 7 days onwards the yolk sac receives quail stem cells emigrating from the embryo.