Catecholamine and acetylcholinesterase distribution in relation to noradrenaline release. An enzyme histochemical and autoradiographic study on the innervation of the cat nictitating muscle.
Catecholamine and acetylcholinesterase distribution in relation to noradrenaline release. An enzyme histochemical and autoradiographic study on the innervation of the cat nictitating muscle.
复制标题
儿茶酚胺和乙酰胆碱酯酶的分布与去甲肾上腺素的释放有关。
DOI：
10.1111/j.1476-5381.1968.tb00428.x
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发表时间：
1968
期刊：
影响因子：
--
通讯作者：
T. Spriggs
中科院分区：
文献类型：
--
作者：
A. Esterhuizen;J. Graham;J. Lever;T. Spriggs
兰利（1900）最初提出支配猫瞬膜的节后交感神经来源于上级颈神经节的胞体。Thompson（1961）支持了这一论点，他证明交感神经通过颈动脉神经从神经节输送，然后通过三叉神经的眶支输送到下瞬目肌和内侧瞬目肌。加德纳、赫尔曼和汤普森（1962）在研究瞬膜的自主神经支配的性质时，描述了哈氏腺有大量的乙酰胆碱酯酶阳性神经，但瞬膜肌内同类纤维的分布非常稀疏。最近，Reynbowitz和Koelle（1965）证明了猫瞬目肌内存在与神经有关的儿茶酚胺和乙酰胆碱酯酶。由于这些以前的研究都没有在精细结构水平上进行，我们已经研究了肾上腺素能和乙酰胆碱酯酶阳性神经的分布与猫瞬膜的光学和电子显微镜，为了进一步检验伯恩和兰德（1959）的重要假设，肾上腺素能神经含有胆碱能机制，其在功能上与去甲肾上腺素的释放相关。
Langley (1900) originally suggested that the postganglionic sympathetic nerves which innervate the cat nictitating membrane are derived from cell bodies in the superior cervical ganglion. This contention was supported by Thompson (1961) who demonstrated that sympathetic nerves are conveyed from the ganglion by the carotid nerve and thence via orbital branches of the trigeminal nerve to the inferior and medial nictitating muscles. Investigating the nature of the autonomic innervation of the nictitating membrane, Gardiner, Hellman & Thompson (1962) described a plentiful supply of acetylcholinesterase-positive nerves to the Harderian gland but a very sparse distribution of the same type of fibres within the nictitating muscles. More recently Jacobowitz & Koelle (1965) have demonstrated the presence of catecholamines and acetylcholinesterase in relation to nerves within cat nictitating muscle. Because none of these previous investigations on the innervation of the nictitating membrane was conducted at a fine structural level we have investigated the distribution of adrenergic and acetylcholinesterase-positive nerves in relation to the cat nictitating muscle by both light and electron microscopy, with a view to testing further the important hypothesis of Burn & Rand (1959) that adrenergic nerves contain a cholinergic mechanism which is functionally related to the release of noradrenaline.