The influence of attentive fixation upon the excitability of the light- sensitive neurons of the posterior parietal cortex
The influence of attentive fixation upon the excitability of the light- sensitive neurons of the posterior parietal cortex
复制标题
注意注视对后顶叶皮层光敏神经元兴奋性的影响
DOI：
10.1523/jneurosci.01-11-01218.1981
复制
发表时间：
1981
影响因子：
15
通讯作者：
B. C. Motter
中科院分区：
文献类型：
--
作者：
V. Mountcastle;R. Andersen;B. C. Motter
我们描述的行为状态后，光敏感（LS）的顶下小叶，7A区，在清醒的猴子研究神经元的兴奋性的影响。顶叶LS神经元对视觉刺激的反应是促进在目标光的注意固定的状态相比，他们的反应，以物理和retinotopically相同的测试刺激期间提供的眼睛暂停的警觉清醒。百分之七十的神经元测试（n = 55）表现出显着的增量反应的状态下的注意固定，增量的中位数为3.5倍。55个细胞中只有4个细胞完全呈现相反的关系。进行了三组对照实验。便利化发生时，在试验过程中引起的反应任务与注意固定的目标相比，由相同的刺激传递到相同的retinotopic位置在每个试验间隔结束时引起的反应：便利化的注意固定是不是由于在一般水平的觉醒的转变。当动物在没有目标光的情况下保持对切线屏幕的一个点的注意固定时，或者当在没有注意固定的情况下在警觉清醒状态下沿着测试刺激呈现模仿目标光的附加光时，会发生易化：易化不是由目标光和测试光之间的感觉-感觉相互作用产生的。最后，观察是否测试刺激的行为相关的促进。我们的结论是，注意固定的行为施加一个特定的和强大的影响后，连接视网膜和顶下小叶的神经系统的兴奋性和促进视觉引导的行为中起着重要的作用。
We describe the effect of behavioral state upon the excitability of light-sensitive (Ls) neurons of the inferior parietal lobule, area 7a, studied in waking monkeys. The responses of parietal LS neurons to visual stimuli are facilitated during the state of attentive fixation of a target light as compared to their responses to physically and retinotopically identical test stimuli delivered during the eye pauses of alert wakefulness. Seventy percent of the neurons tested (n = 55) showed significant increments in responses in the state of attentive fixation; the median value of the increments was 3.5 times. Only 4 of the 55 cells examined completely showed the reverse relation. Three sets of control experiments were done. The facilitation occurred when the responses evoked during the trials of a reaction task with attentive fixation of a target were compared with those evoked by identical stimuli delivered to the same retinotopic locations at the end of each intertrial interval: the facilitation of attentive fixation is not due to a shift in the general level of arousal. The facilitation occurred when the animal maintained attentive fixation of a spot of the tangent screen without a target light or when an additional light mimicking the target light was presented along with testing stimuli in the state of alert wakefulness without attentive fixation: the facilitation is not produced by a sensory-sensory interaction between target and testing lights. Finally, the facilitation was observed whether or not the test stimuli were behaviorally relevant. We conclude that the act of attentive fixation exerts a specific and powerful effect upon the excitability of the neural systems linking the retinae and the inferior parietal lobule and that the facilitation plays an important role in visually guided behavior.
DOI：
10.1016/0013-4694(80)90222-9
发表时间：
1980-01-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
HANSEN, JC;HILLYARD, SA
通讯作者：
HILLYARD, SA