Molecular genetics of lipoprotein (a): new pieces to the puzzle.
Molecular genetics of lipoprotein (a): new pieces to the puzzle.
复制标题
脂蛋白的分子遗传学 (a)：新的难题。
DOI：
10.1097/00041433-199404000-00012
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发表时间：
1994
影响因子：
4.4
通讯作者：
Hobbs,HH
中科院分区：
文献类型：
--
作者：
Gaw,A;Hobbs,HH
在过去的一年里，我们在理解脂蛋白(A)[Lp(A)]的遗传学方面取得了重要进展。载脂蛋白(A)[APO(A)]基因已被克隆，并通过基因工程使小鼠表达载脂蛋白(A)和脂蛋白(A)。这些进展为回答Lp(A)的遗传学、新陈代谢和致动脉粥样硬化等许多基本问题提供了工具。
Important advances have been made in the past year in our understanding of the genetics of lipoprotein (a)[Lp (a)]. The apolipoprotein (a)[APO (a)] gene has been cloned and mice have been engineered to express apo (a) and Lp (a). These developments have provided the tools to answer many fundamental questions concerning the genetics, metabolism, and atherogenicity of Lp (a).