EcoCyc: fusing model organism databases with systems biology.

EcoCyc: fusing model organism databases with systems biology.
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DOI:
10.1093/nar/gks1027
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发表时间:
2013-01
影响因子:
14.9
通讯作者:
Karp PD
Karp PD
中科院分区:
生物学2区
文献类型:
--
作者:
Keseler IM;Mackie A;Peralta-Gil M;Santos-Zavaleta A;Gama-Castro S;Bonavides-Martínez C;Fulcher C;Huerta AM;Kothari A;Krummenacker M;Latendresse M;Muñiz-Rascado L;Ong Q;Paley S;Schröder I;Shearer AG;Subhraveti P;Travers M;Weerasinghe D;Weiss V;Collado-Vides J;Gunsalus RP;Paulsen I;Karp PD

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EcoCyc(http://EcoCyc.org)是一个基于大肠杆菌K - 12 MG1655基因组序列构建的模式生物数据库。在EcoCyc中,对单个大肠杆菌基因产物功能的专家人工注释是基于在大肠杆菌K - 12衍生菌株的实验文献中发现的信息。EcoCyc内容的更新持续完善大肠杆菌生物学的全貌。EcoCyc网站上提供的新工具增强了EcoCyc的实用性,并且EcoCyc作为一种教学工具的开发正在增加EcoCyc中所收集知识的影响力。
EcoCyc (http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived strains. Updates to EcoCyc content continue to improve the comprehensive picture of E. coli biology. The utility of EcoCyc is enhanced by new tools available on the EcoCyc web site, and the development of EcoCyc as a teaching tool is increasing the impact of the knowledge collected in EcoCyc.
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