Antibiotic-Induced Neurotoxicity
Antibiotic-Induced Neurotoxicity
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DOI：
10.1007/s11908-014-0448-3
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发表时间：
2014-12-01
影响因子：
3.1
通讯作者：
Berkowitz, Aaron L.
中科院分区：
文献类型：
--
作者：
Bhattacharyya, Shamik;Darby, Ryan;Berkowitz, Aaron L.
抗生素神经毒性是罕见的，但当它发生时会导致严重的发病率。抗生素神经毒性的风险似乎在年龄较大、肾功能受损或已有神经系统疾病的患者中最高。本文综述了影响神经系统的最常见抗生素毒性的临床特征：癫痫发作、脑病、视神经病变、周围神经病变和重症肌无力加重。
Antibiotic neurotoxicity is rare but can cause significant morbidity when it occurs. The risk of antibiotic neurotoxicity appears to be highest in patients who are older, have impaired renal function, or have preexisting neurologic conditions. This review describes the clinical features of the most common antibiotic toxicities affecting the nervous system: seizures, encephalopathy, optic neuropathy, peripheral neuropathy, and exacerbation of myasthenia gravis.