Prognostic significance of c-ABL methylation in chronic myelogenous leukemia: still an open question.
Prognostic significance of c-ABL methylation in chronic myelogenous leukemia: still an open question.
复制标题
c-ABL 甲基化在慢性粒细胞白血病中的预后意义：仍然是一个悬而未决的问题。
作者：
F. Asimakopoulos;P. J. Shteper;E. Fibach;E. Rachmilewitz;Y. Ben;D. Ben
致编辑：
To the Editor:
Methylation of the proximal promoter of the c- ABL oncogene is a specific epigenetic alteration associated with progression of chronic phase chronic myelogenous leukemia (CML) to accelerated and blastic phases.[1-6][1] A recent report by Issa et al[6][2]published in Blood concludes
ABL 和 BCRABL 蛋白对正常和白血病骨髓细胞增殖和基因毒性应激反应的拮抗作用。
影响因子：
2.6
作者：
Guo,XY;Fontana,J;Kufe,D;Deisseroth,A
通讯作者：
Deisseroth,A