Reaction of rat connective tissue to implanted dentin tubes filled with mineral trioxide aggregate or calcium hydroxide

Reaction of rat connective tissue to implanted dentin tubes filled with mineral trioxide aggregate or calcium hydroxide
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DOI:
10.1016/s0099-2399(99)80134-4
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发表时间:
1999-03-01
影响因子:
4.2
通讯作者:
Dezan, E
Dezan, E
中科院分区:
医学2区
文献类型:
--
作者:
Holland, R;de Souza, V;Dezan, E

文献摘要

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本研究观察了大鼠皮下结缔组织对氢氧化钙和无机三氧化物复合体牙本质管的反应。分别于术后7天和30天处死动物,制备标本进行形态学研究。取部分未脱钙标本,用偏振光和Von Kossa技术进行钙的组织学分析。两种研究材料的结果相似。在管开口处,存在对偏振光呈双折射的Von Kossa阳性颗粒。在这些颗粒旁边,有一个像桥一样的不规则组织,是Von Kossa阳性的。牙本质管壁在牙本质小管中表现出对偏振光高度双折射的结构,通常像一层,在不同的深度。这两种材料的作用机制可能具有一定的相似性。
This study was conducted to observe the rat subcutaneous connective tissue reaction to the implanted dentin tubes filled with calcium hydroxide or mineral trioxide aggregate. The animals were sacrificed after 7 and 30 days, and the specimens were prepared for morphological study. Some undecalcified specimens were prepared for histological analysis with polarized light and Von Kossa technique for calcium. The results were similar for both studied materials. At the tube openings, there were Von Kossa-positive granules that were birefringent to polarized light. Next to these granulations, there was an irregular tissue like a bridge that was Von Kossa-positive. The dentin walls of the tubes exhibited in the tubules a structure highly birefringent to polarized light, usually like a layer and at different depths. It is possible that the mechanism of action of both materials has some similarity.