The Best Single Measurement for Assessing Splenomegaly in Patients with Cirrhotic Liver Morphology
The Best Single Measurement for Assessing Splenomegaly in Patients with Cirrhotic Liver Morphology
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DOI：
10.1016/j.acra.2017.06.006
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发表时间：
2017-12-01
影响因子：
4.8
通讯作者：
Bhatt, Shweta
中科院分区：
文献类型：
--
作者：
Nuffer, Zachary;Marini, Thomas;Bhatt, Shweta
基本原理和目标：放射学文献中对于评估脾肿大的最佳单一测量方法几乎没有达成一致。在本研究中，我们评估了多次单向测量的脾脏与计算机断层扫描（CT）肝硬化肝脏形态患者的脾体积的相关性。 材料和方法：通过 179 名成年患者的 CT 检查回顾性计算脾体积，其中 47 名患者被批准为肾供者，其中 132 名患者因各种其他适应症转诊，并在 CT 上发现肝硬化肝脏形态。对每个脾脏进行七个一维测量（长轴、头尾、宽度和四个厚度测量），以确定哪一个与计算体积最密切相关。结果：对于轻至中度脾肿大，脾宽度与脾体积具有最佳相关性，对于大量脾肿大，脾头尾测量与脾体积具有最佳相关性。接受者操作特征分析表明，约 10.5 cm 的脾宽度测量值对于轻中度脾肿大的敏感性为 89%，特异性为 78%，而头尾测量值 14.6 cm 对于大量脾肿大的敏感性为 92%，特异性为 91%。 结论： 10.5 cm 的脾宽度阈值是最敏感的(89%) 和特异性 (78%) 的单次测量对于肝硬化肝脏形态患者的轻度至中度脾肿大来说，而头尾高度阈值 14.6 cm 是对于巨脾肿大最敏感 (92%) 和特异性 (91%) 的单次测量。 (C) 2017 年大学放射科医生协会。由爱思唯尔公司出版。保留所有权利。
Rationale and Objectives: There is little agreement within the radiology literature as to the best single measurement for assessing splenomegaly. In this study, we evaluate the correlation of multiple unidirectional measurements of the spleen with splenic volume in patients with cirrhotic liver morphology on computed tomography (CT).Materials and Methods: Splenic volume was retrospectively calculated from CT examinations of 179 adult patients, 47 of whom were approved as renal donors, and 132 of whom were referred for various other indications, and were found to have cirrhotic liver morphology on CT. Seven unidimensional measurements (long-axis, cranial-caudal, width, and four measures of thickness) of each spleen were evaluated to identify which most closely correlated with the calculated volume.Results: The splenic width had the best correlation with splenic volume for mild-to-moderate splenomegaly, and the splenic cranial caudal measurement had the best correlation with splenic volume for massive splenomegaly. Receiver operating characteristic analysis demonstrates that a splenic width measurement of approximately 10.5 cm has a sensitivity of 89% and a specificity of 78% for mild to-moderate splenomegaly, and a cranial-caudal measurement of 14.6 cm has a sensitivity of 92% and a specificity of 91% for massive splenomegaly.Conclusions: A splenic width threshold of 10.5 cm is the most sensitive (89%) and specific (78%) single measurement for mild-to moderate splenomegaly in patients with cirrhotic liver morphology, whereas a cranial-caudal height threshold of 14.6 cm is the most sensitive (92%) and specific (91%) single measurement for massive splenomegaly. (C) 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.