Continuous-wave laser-assisted injection of single magnetic nanobeads into living cells
Continuous-wave laser-assisted injection of single magnetic nanobeads into living cells
复制标题
DOI：
10.1016/j.snb.2016.01.149
复制
发表时间：
2016-07-01
影响因子：
8.4
通讯作者：
Arai, Fumihito
中科院分区：
文献类型：
--
作者：
Zhong, Jing;Liu, Hengjun;Arai, Fumihito
将珠子/分子快速有效地运输到具有高细胞活力的活细胞中对于药物开发和细胞生物学至关重要。这项研究提出了一种使用连续波激光将表面温度较低的单个磁性纳米珠注入活细胞的新方法。实验结果表明，磁性纳米珠成功注射到活细胞中，注射率高达100%，注射时间短，约1 s，最大细胞存活率达100%。 (C) 2016 Elsevier B.V. 保留所有权利。
Fast and effective transportation of beads/molecules into living cells with high cell viability is essential for drug development and cell biology. This study presents a new approach of injecting single magnetic nanobeads with low surface temperature into living cells using a continuous-wave laser. Experimental results demonstrate the successful injection of magnetic nanobeads into living cells with high injection rates reaching 100%, short injection times of about 1 s, and maximal cell survival rates of 100%. (C) 2016 Elsevier B.V. All rights reserved.