Weight loss and asthma control in severely obese asthmatic females
Weight loss and asthma control in severely obese asthmatic females
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DOI：
10.1016/j.rmed.2007.07.029
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发表时间：
2008-01-01
影响因子：
4.3
通讯作者：
Sofia, Matteo
中科院分区：
文献类型：
--
作者：
Maniscalco, Mauro;Zedda, Anna;Sofia, Matteo
背景：肥胖被认为是严重呼吸紊乱（包括哮喘）的重要易感因素。持续减肥对哮喘控制的影响还不太清楚。我们调查了减肥手术引起的体重减轻对哮喘控制严重肥胖asthma patients.Patients和方法的影响：一个连续系列的12个哮喘肥胖女性腹腔镜可调胃束带（OB组）和10个非操作哮喘肥胖女性作为对照组（CG）。结果：OB组平均体重指数（kg/m2）从术前45.2 ± 4.7降至术后34.8 ± 4.2。手术后OB组的ACT评分从18.7分显著提高到22.2分（p
Background: Obesity is proposed to represent an important predisposing condition to serious respiratory disturbances including asthma. The effects of consistent weight toss on asthma control are not well known. We investigated the effect of weight reduction induced by bariatric surgery on asthma control in severely obese asthmatic patients.Patients and methods: A consecutive series of 12 asthmatic obese females who had laparoscopic adjustable gastric banding (OB group) and 10 non-operated asthmatic obese females as control group (CG). Body mass index (BMI), Asthma Control Test (ACT), pulmonary function test (PFT), exhaled nitric oxide (NO) were evaluated at baseline and after 1 year.Results: Mean BMI (kg/m(2)) of OB group decreased from 45.2 +/- 4.7 before surgery to 34.8 +/- 4.2 post-operatively. After surgery the overall ACT score in OB group significantly improved from 18.7 to 22.2 (p