Clinically acceptable restorations may be a hotbed for cariogenic microbes
Clinically acceptable restorations may be a hotbed for cariogenic microbes
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临床上可接受的修复体可能是致龋微生物的温床
DOI：
10.1111/j.1741-2358.2011.00571.x
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发表时间：
2011
期刊：
影响因子：
2
通讯作者：
Ebisu S
中科院分区：
文献类型：
--
作者：
Ogawa T;Ikebe K;Murai S;Enoki K;Maeda Y;Imazato S;Ebisu S
DOI：10.1111/j.1741-2358.2011.00571.x临床可接受的修复体可能是致龋菌的温床目的：本研究的目的是调查老年人口腔修复体与唾液致龋性病原体的横断面相关性，以建立该人群龋病风险的有效参数。材料和方法：采集289名社区老年人(66.2 ± 3.9 )的唾液，这些老年人有20颗以上的牙齿。采用实时定量聚合酶链式反应(Real-time PCR)技术检测唾液中3种致龋菌(变形链球菌、远缘链球菌和乳杆菌)的致龋率。结果：修复牙平均残牙26.4颗，冠、嵌体和复合树脂修复牙分别为7.35颗、3.88颗和0.68颗。冠数与唾液中变形链球菌、深水葡萄球菌和乳杆菌呈正相关。多元线性回归分析显示，在控制了年龄、性别、残牙数量和唾液流率后，修复牙的数量与唾液流率、变形链球菌、深红葡萄球菌和乳杆菌独立相关。唾液流率与唾液S、变形杆菌和乳酸菌独立相关。结论：牙冠数与唾液中致龋菌水平存在相关性，提示该参数可能是老年人群龋病的危险指标。
doi: 10.1111/j.1741‐2358.2011.00571.xClinically acceptable restorations may be a hotbed for cariogenic microbesObjective:The aim of this study was to investigate the cross‐sectional association of dental restorations with salivary cariogenic pathogens among the elderly to establish effective parameters of caries risk for this population.Materials and methods:Stimulated whole saliva was collected from 289 community‐dwelling older adults (66.2 ± 3.9 years old) who had 20 or more teeth. Salivary levels of three cariogenic bacteria (Streptococcus mutans,Streptococcus sobrinusand lactobacilli) were estimated using quantitative polymerase chain reaction (real‐time PCR) method.Results:The mean number of residual teeth was 26.4, and restored teeth with crowns, inlays and composite resin were 7.35, 3.88 and 0.68, respectively. The number of crowns correlated positively with salivaryS. mutans,S. sobrinusand lactobacilli. Multiple linear regression analyses showed that the number of restored teeth with crowns was independently associated with salivaryS. mutans,S. sobrinusand lactobacilli after controlling for age, gender, number of residual teeth and salivary flow rate. Salivary flow rate was independently associated with salivaryS. mutansand lactobacilli.Conclusion:The number of crowns had an association with salivary levels of cariogenic bacteria, suggesting that this parameter may be a caries risk indicator for the elderly population.