Chapter 8:The CYP2D Subfamily
Chapter 8:The CYP2D Subfamily
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第 8 章：CYP2D 亚家族
DOI：
10.1039/9781847558428-00241
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
U. Zanger
中科院分区：
文献类型：
--
作者：
U. Zanger
人细胞色素P450（CYP2D6）是第一个在相应基因和蛋白质被鉴定之前几年就知道经典药物遗传学多态性的细胞色素P450。通过临床观察，抗妊娠、催产药鹰爪豆碱和抗高血压药对妊娠结局有较好的疗效。
The human cytochrome P450 (CYP) 2D6 was the first cytochrome P450 for which a classical pharmacogenetic polymorphism became known several years before the corresponding gene and protein were identified. By way of clinical observations, the antiarrhythmic and oxytocic drug sparteine and the antihyper...