Plasma Norepinephrine, Epinephrine, and Dopamine Levels in End-Stage Renal Disease: Effect of Hemodialysis

Plasma Norepinephrine, Epinephrine, and Dopamine Levels in End-Stage Renal Disease: Effect of Hemodialysis
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终末期肾病中的血浆去甲肾上腺素、肾上腺素和多巴胺水平:血液透析的影响

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发表时间:
1985
期刊:
影响因子:
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通讯作者:
M. Maksy
M. Maksy
中科院分区:
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文献类型:
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作者:
A. Elias;N. Vaziri;M. Maksy

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• The effect of hemodialysis on plasma norepinephrine (NE), epinephrine, and dopamine levels was studied in 11 patients undergoing maintenance hemodialysis. The results showed that the baseline plasma concentrations of NE and dopamine were significantly elevated in patients with end-stage renal disease undergoing maintenance hemodialysis. Intradialysis weight loss and fall in the serum glucose concentration during dialysis correlated with changes in plasma epinephrine and NE concentrations. Single-pass dialysis resulted in a marked reduction in the plasma NE concentration, indicating significant removal by dialysis. These observations should be taken into consideration when interpreting plasma catecholamine data obtained in the course of investigation of hypertensive patients with end-stage renal disease. ( Arch Intern Med 1985;145:1013-1015)