Degeneracy and complexity in biological systems

Degeneracy and complexity in biological systems
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DOI:
10.1073/pnas.231499798
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发表时间:
2001-11-20
影响因子:
11.1
通讯作者:
Gally, JA
Gally, JA
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Edelman, GM;Gally, JA

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简并性,即结构不同的元件执行相同功能或产生相同输出的能力,是遗传密码和免疫系统的众所周知的特征。在这里,我们指出,简并性是一个普遍存在的生物学特性,并认为它是在遗传,细胞,系统和人口水平的复杂性的一个特征。此外,它既是自然选择的必要条件,也是自然选择的必然结果。
Degeneracy, the ability of elements that are structurally different to perform the same function or yield the same output, is a well known characteristic of the genetic code and immune systems. Here, we point out that degeneracy is a ubiquitous biological property and argue that it is a feature of complexity at genetic, cellular, system, and population levels. Furthermore, it is both necessary for, and an inevitable outcome of, natural selection.