Central oscillators responsible for sympathetic nerve discharge.
Central oscillators responsible for sympathetic nerve discharge.
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负责交感神经放电的中枢振荡器。
DOI：
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发表时间：
1980
影响因子：
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通讯作者：
G. L. Gebber
中科院分区：
文献类型：
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作者：
G. L. Gebber
研究了有关交感神经中产生背景放电的中枢机制的当前知识状况。从最近的研究中可以明显看出，由外部输入强加节律（心脏和呼吸相关）的随机放电和分散组织的中央网络的经典概念尚未通过时间的考验。相反，控制交感神经放电的脑干和脊髓网络本质上具有产生节律的能力。中枢神经系统固有的交感神经节律意味着存在能够振荡活动的神经元回路。中枢振荡器提供了一种在没有来自中枢神经系统外源的周期性输入的情况下同步交感神经元群活动的机制。事实上，该论文的发展是，来自外部源（例如压力感受器）的周期性输入的功能不是在交感神经放电中产生节律，而是夹带中枢起源的节律。最后，讨论了与识别包含控制交感神经放电的中枢振荡器的神经元类型相关的问题。
The current state of knowledge concerning central mechanisms responsible for the generation of background discharges in sympathetic nerves is examined. It is apparent from recent investigations that the classic concept of a randomly discharging and diffusely organized central network onto which rhythms (cardiac- and respiratory-related) are imposed by extrinsic inputs has not passed the test of time. Rather, brain stem as well as spinal networks that govern the discharges of sympathetic nerves are inherently capable of rhythm generation. Sympathetic nerve rhythms inherent to the central nervous system imply the existence of neuronal circuits that are capable of oscillatory activity. Central oscillators provide a mechanism for synchronization of the activity of populations of sympathetic neurons in the absence of periodic input from sources extrinsic to the central nervous system. Indeed, the thesis is developed that, rather than creating rhythms in sympathetic nerve discharge, the function of periodic input from extrinsic sources such as the baroreceptors is to entrain rhythms of central origin. Finally, the problems associated with the identification of neuronal types that comprise central oscillators which govern the discharges of sympathetic nerves are discussed.