The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database
The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database
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DOI：
10.1007/s12149-009-0331-8
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发表时间：
2010-02-01
影响因子：
2.6
通讯作者：
Okuda, Koichi
中科院分区：
文献类型：
--
作者：
Nakajima, Kenichi;Matsuo, Shinro;Okuda, Koichi
日本核医学学会（JSNM）工作组创建了一个适用于标准采集方案的心肌灌注成像数据库。本研究的目的是验证普通标准数据库的诊断准确性与各研究所的专家解释相比较。五家机构参与了这项研究，使用了不同的采集设置，包括360A /180A度旋转，摄像机配置和摄像机轨道。各个机构使用的软件及其版本也各不相同。应用工作组数据库从共166例冠心病（CAD）患者和145例低可能性冠心病患者中检测罪魁祸首冠状动脉区域。当总压力评分为千分之一（a parts per thousand yen4）定义为显著异常时，基于普通数据库的定量分析的总体敏感性、特异性和准确性分别为77、72和75%，而机构视觉专家阅读的总体敏感性、特异性和准确性分别为72、79和75%。该公共数据库由一个多中心工作组创建，并以180/360度采集对男性/女性进行区分，显示出与每个研究所的专家解释相当的诊断准确性，并且它可能适用于多中心研究。
The Japanese Society of Nuclear Medicine (JSNM) working group has created a myocardial perfusion imaging database applicable to standard acquisition protocol. The aim of this study is to validate the diagnostic accuracy of the common normal database compared with the expert interpretation of each institute.Five institutions participated in this study and used different acquisition settings which included 360A degrees/180A degrees rotation, camera configuration and camera orbits. The software and its version used in each institution also varied. The working group database was applied to detect the culprit coronary territory from a total of 166 patients with coronary artery disease (CAD) and 145 patients with low-likelihood of CAD.When summed stress score a parts per thousand yen4 was defined as significant abnormality, overall sensitivity, specificity and accuracy of patient-based analysis were 77, 72 and 75%, respectively, based on quantitative analysis using the common database, whereas those by institutional visual expert reading were 72, 79 and 75%, respectively.The common database, which was created by a multi-center working group and separated between male/female with 180/360A degrees acquisitions, demonstrated comparable diagnostic accuracy to expert interpretation by each institute, and it may be applicable to multi-center studies.