A multicentre, randomised, sham-controlled trial on REmote iSchemic conditioning In patients with acute STroke (RESIST) - Rationale and study design

A multicentre, randomised, sham-controlled trial on REmote iSchemic conditioning In patients with acute STroke (RESIST) - Rationale and study design
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DOI:
10.1177/2396987319884408
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发表时间:
2019-10-25
影响因子:
6.1
通讯作者:
Andersen, Grethe
Andersen, Grethe
中科院分区:
医学3区
文献类型:
--
作者:
Blauenfeldt, Rolf A.;Hjort, Niels;Andersen, Grethe

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基本原理 在院前环境中应用并在院内持续进行远程缺血调理,可以改善急性缺血性中风和脑出血患者的功能结果。目的 评估联合远程缺血预适应和后适应是否可以改善急性缺血性卒中和脑出血患者的长期功能结果。方法和设计丹麦多中心、前瞻性、随机、患者评估者盲法、假对照研究。疑似中风的成年患者院前确定症状持续时间
Rationale Remote ischaemic conditioning, applied in the prehospital setting and continued in-hospital, may improve functional outcome in patients with acute ischaemic stroke and intracerebral haemorrhage. Aims To evaluate whether combined remote ischaemic per- and postconditioning can improve long-term functional outcome in acute ischaemic stroke and intracerebral haemorrhage patients. Methods and design Danish multicentre, prospective, randomised, patient-assessor blinded, sham-controlled study. Adult patients with a putative stroke identified prehospital with symptom duration