Distribution of electrical stimulation current in a planar multilayer anisotropic tissue
Distribution of electrical stimulation current in a planar multilayer anisotropic tissue
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DOI：
10.1109/tbme.2007.902248
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发表时间：
2008-02-01
影响因子：
4.6
通讯作者：
Merletti, Roberto
中科院分区：
文献类型：
--
作者：
Mesin, Luca;Merletti, Roberto
这项研究分析性地解决了生理组织（称为体积导体）的平面、多层、各向异性模型的神经肌肉电刺激问题。体积导体的电导率和介电常数都被考虑，包括色散特性。解析解是在二维傅立叶变换域中获得的，在平行于体积导体表面的平面中进行变换。该模型在计算成本方面是高效的，因为解决方案是解析的（仅需要数值傅里叶反演）。它提供了由皮肤表面传递的电流引起的生理组织中的电流分布。考虑该模型应用的三个代表性示例。 1）经皮电刺激和肌电图检测过程中刺激伪影的模拟。仅考虑体积导体的影响，忽略其他伪影来源（例如刺激电极和记录电极之间的电容耦合）。 2）模拟不同刺激频率的正弦刺激电流的肌肉内电流分布以及体积导体的低通滤波效果。 3) 估计肌肉内用于干扰刺激的调幅电流分布。该模型致力于模拟神经肌肉刺激，但相同的方法也可以应用于其他领域，在这些领域中，对从介质边界注入电流引起的介质中电流分布的估计是感兴趣的。
This study analytically addresses the problem of neuromuscular electrical stimulation for a planar, multilayer, anisotropic model of a physiological tissue (referred to as volume conductor). Both conductivity and permittivity of the volume conductor are considered, including dispersive properties. The analytical solution is obtained in the 2-D Fourier transform do- main, transforming in the planes parallel to the volume conductor surface. The model is efficient in terms of computational cost, as the solution is analytical (only numerical Fourier inversion is needed). It provides the current distribution in a physiological tissue induced by an electrical current delivered at the skin surface. Three representative examples of application of the model are considered. 1) The simulation of stimulation artefact during transcutaneous electrical stimulation and EMG detection. Only the effect of the volume conductor is considered, neglecting the other sources of artefact (such as the capacitive coupling between the stimulating and recording electrodes). 2) The simulation of the electrical current distribution within the muscle and the low-pass filter effect of the volume conductor on sinusoidal stimulation currents with different stimulation frequencies. 3) The estimation of the amplitude modulated current distribution within the muscle for interferential stimulation. The model is devoted to the simulation of neuromuscular stimulation, but the same method could be applied in other fields in which the estimation of the electrical current distribution in a medium induced by the injection of a current from the boundary of the medium is of interest.