Preliminary evidence for neural responsiveness to infants in mothers with schizophrenia and the implications for healthy parenting.
Preliminary evidence for neural responsiveness to infants in mothers with schizophrenia and the implications for healthy parenting.
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精神分裂症母亲对婴儿的神经反应的初步证据及其对健康育儿的影响。
DOI：
10.1016/j.schres.2017.11.033
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发表时间：
2018
影响因子：
4.5
通讯作者：
Abel KM
中科院分区：
文献类型：
--
作者：
Abel KM
精神分裂症是一种严重的精神疾病，可能会严重影响母亲的敏感行为。母亲行为的神经相关性代表了一种潜在的有价值的手段，可以客观地区分表达母亲敏感性差异的健康母亲。由于与健康母亲相比，患有精神分裂症（MWS）的母亲对婴儿的行为反应存在缺陷，因此我们探讨了患有精神分裂症（MWS）的母亲大脑对婴儿刺激的反应是否会显着降低。我们还研究了健康母亲和患病母亲之间（在与自己的婴儿玩耍互动期间）母亲行为的差异是否与婴儿刺激下的大脑激活差异相关。我们没有发现 11 名新 MWS 与 20 名健康新妈妈相比，“母亲大脑”反应或“母亲行为”反应存在差异的证据；对婴儿的神经反应也与 MWS 中母亲与婴儿关系的行为或认知方面无关。这些初步结果表明，MWS 和健康母亲之间的母亲敏感性差异（先前的研究表明）在稳定治疗的 MWS 中可能是可逆的。
Schizophrenia is a severe mental illness that may significantly affect maternal sensitive behaviour. Neural correlates of maternal behaviour represent a potentially valuable means of differentiating objectively between healthy mothers expressing variations in maternal sensitivity. As mothers with schizophrenia (MWS) show deficits in behavioural responses to infants compared to healthy mothers, we explored whether maternal brain responses to infant stimuli would be significantly reduced in MWS. We also examined whether differences in maternal behaviour between healthy and ill mothers (during play interactions with own infant) were associated with differences in brain activation to infant stimuli.We found no evidence of differential ‘maternal brain’ responses or ‘maternal behavioural’ responses in 11 new MWS compared to 20 healthy new mums; neither were neural responses to infants linked to behavioural or cognitive aspects of the mother's relationship with her infant in MWS. These preliminary findings suggest maternal sensitivity differences between MWS and healthy mothers, suggested in previous studies, may be reversible in stable treated MWS.