Choosing Goals, Not Rules: Deciding among Rule-Based Action Plans
Choosing Goals, Not Rules: Deciding among Rule-Based Action Plans
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DOI：
10.1016/j.neuron.2011.02.053
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发表时间：
2011-05-12
期刊：
影响因子：
16.2
通讯作者：
Gail, Alexander
中科院分区：
文献类型：
--
作者：
Klaes, Christian;Westendorff, Stephanie;Gail, Alexander
在自然情况下，运动通常指向与引起感官刺激的位置不同的位置。然后，必须根据规则从感官提示中推断出运动目标。当适用于给定提示的规则存在不确定性时，规划运动涉及“选择相关规则并根据该规则计算运动目标”。在这些条件下，尚不清楚灵长类动物在选择动作之前是否会根据所有可能的规则计算多个运动目标，或者它们是否首先选择一个规则，然后仅表示与该规则相关的运动目标。支持前一个假设，我们表明猴子额顶叶区域的神经元同时代表两个不同的基于规则的运动目标，这些目标受到猴子的选择偏好的影响。显然，灵长类动物通过权衡与每个选项相关的运动目标，在多种行为选项之间进行选择。
In natural situations, movements are often directed toward locations different from that of the evoking sensory stimulus. Movement goals must then be inferred from the sensory cue based on rules. When there is uncertainty about the rule that applies for a given cue, planning a movement involves both 'Choosing the relevant rule and computing the movement goal based on that rule. Under these conditions, it is not clear whether primates compute multiple movement goals based on all possible rules before choosing an action, or whether they first choose a rule and then only represent the movement goal associated with that rule. Supporting the former hypothesis, we show that neurons in the frontoparietal reach areas of monkeys simultaneously represent two different rule-based movement goals, which are biased by the monkeys' choice preferences. Apparently, primates choose between multiple behavioral options by weighing against each other the movement goals associated with each option.