Base pairs and pseudo pairs observed in RNA-ligand complexes
Base pairs and pseudo pairs observed in RNA-ligand complexes
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DOI：
10.1002/jmr.978
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发表时间：
2010-03-01
影响因子：
2.7
通讯作者：
Westhof, Eric
中科院分区：
文献类型：
--
作者：
Kondo, Jiro;Westhof, Eric
以前，提出了一种几何命名法，其中RNA碱基对通过它们的相互作用边（沃森-克里克，胡斯汀或糖边）和相对于形成的氢键的糖苷键方向（顺式或反式）来分类。这里，在RNA-配体复合物中观察到的碱基对和假对以类似的方式分类。21个基本几何家族在几何学上是可能的（18个用于核酸碱基和含有杂环的配体之间形成的碱基对，3个家族用于伪对）。其中16个已经在X射线和/或NMR结构中观察到。版权所有（C）2009约翰威利父子有限公司
Previously, a geometric nomenclature was proposed in which RNA base pairs were classified by their interaction edges (Watson-Crick, Hoogsteen or sugar-edge) and the glycosidic bond orientations relative to the hydrogen bonds formed (cis or trans). Here, base pairs and pseudo pairs observed in RNA-ligand complexes are classified in a similar manner. Twenty-one basic geometric families are geometrically possible (18 for base pairs formed between a nucleic acid base and a ligand containing heterocycle and 3 families for pseudo pairs). Of those, 16 of them have been observed in X-ray and/or NMR structures. Copyright (C) 2009 John Wiley & Sons, Ltd.