Global dynamics of a cholera model with age structures and multiple transmission modes
Global dynamics of a cholera model with age structures and multiple transmission modes
复制标题
具有年龄结构和多种传播模式的霍乱模型的全球动态
DOI:
10.1142/s1793524519500517
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发表时间:
2019-08
影响因子:
2.2
通讯作者:
Chen Yuming
中科院分区:
文献类型:
--
作者:
Wang Xia;Chen Yuming
In this paper, we propose and analyze a cholera model. The model incorporates both direct transmission (person-to-person transmission) and indirect transmission (contaminated environment-to-person transmission: hyper-infectivity and lower-infectivity). Moreover, we employ general nonlinear incidences and introduce infection age of infectious individuals and biological ages of pathogens in the environment. After considering the well-posedness of the system, we study the existence and local stability of steady states, which is determined by the basic reproduction number. To establish the attractivity of the infection steady state, we also get the uniform persistence and existence of compact global attractors. The main result is a threshold dynamics obtained by applying the Fluctuation Lemma and the approach of Lyapunov functionals. When the basic reproduction number is less than one, the infection-free steady state is globally asymptotically stable while when the basic reproduction number is larger than one, the infection steady state attracts each solution with nonzero infection force at some time point. The effect of multiple transmission modes on the disease dynamics is also discussed.
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