Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform
Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform
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DOI：
10.1161/hy1001.096106
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发表时间：
2001-10-01
期刊：
影响因子：
8.3
通讯作者：
Kon, ND
中科院分区：
文献类型：
--
作者：
Pauca, AL;O'Rourke, MF;Kon, ND
上肢中的压力波反射引起动脉脉搏放大，使得径向收缩压和脉搏压大于升主动脉中的压力。在成年人中，上肢（与降主动脉和下肢相反）的波传输特性几乎不随年龄、疾病和药物治疗而变化。这种一致性导致使用广义传递函数来从桡动脉脉搏合成升主动脉压力脉搏。这种方法的有效性进行了测试，估计主动脉收缩压，舒张压，脉搏，和平均压力的径向压力波形。升主动脉和桡动脉压力波形同时记录在心脏手术，开始心肺转流术前，与匹配的，充满液体的压力计系统在控制条件下，在硝酸甘油输注62例。由桡动脉脉搏产生的主动脉压力脉搏波与测量的主动脉脉搏波在收缩压、舒张压、脉搏压和平均压方面一致，平均差异
Pressure wave reflection in the upper limb causes amplification of the arterial pulse so that radial systolic and pulse pressures are greater than in the ascending aorta. Wave transmission properties in the upper limbs (in contrast to the descending aorta and lower limbs) change little with age, disease, and drug therapy in adult humans. Such consistency has led to use of a generalized transfer function to synthesize the ascending aortic pressure pulse from the radial pulse. Validity of this approach was tested for estimation of aortic systolic, diastolic, pulse, and mean pressures from the radial pressure waveform. Ascending aortic and radial pressure waveforms were recorded simultaneously at cardiac surgery, before initiation of cardiopulmonary bypass, with matched, fluid-filled manometer systems in 62 patients under control conditions and during nitroglycerin infusion. Aortic pressure pulse waves, generated from the radial pulse, showed agreement with the measured aortic pulse waves with respect to systolic, diastolic, pulse, and mean pressures, with mean differences