CHEMICAL ASPECTS OF MUCUS

CHEMICAL ASPECTS OF MUCUS
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DOI:
10.1093/oxfordjournals.bmb.a071455
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发表时间:
1978-01-01
影响因子:
6.7
通讯作者:
ROBERTS, GP
ROBERTS, GP
中科院分区:
医学2区
文献类型:
--
作者:
CLAMP, JR;ALLEN, A;ROBERTS, GP

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正如 Reid 和 Clamp (1978) 在本公报中所讨论的,粘液糖蛋白是高分子量蛋白质,拥有数百个(如果不是数千个)共价连接的寡糖单元。这些单元平均含有约 8-10 个五种不同类型的单糖残基。这些如下,括号内给出不同的系统名称:L-岩藻糖(6-脱氧-L-半乳糖); D-半乳糖; N-乙酰基-D-葡萄糖胺(2-乙酰氨基-2-脱氧-D-葡萄糖); N-乙酰基-D-半乳糖胺(2-乙酰氨基-2-脱氧-r>半乳糖);和唾液酸。唾液酸是任何取代的神经氨酸的总称。在人类中,唯一重要的唾液酸是//-乙酰神经氨酸(5-acetamido-3, 5-
As discussed in the present Bulletin by Reid & Clamp (1978), mucus glycoproteins are high-molecular-weight proteins possessing many hundreds, if not thousands, of covalently attached oligosaccharide units. The units contain on average about 8-10 monosaccharide residues of five different types. These are as follows, with the systematic name where different given in parentheses: L-fucose (6-deoxy-L-galactose); D-galactose; N-acetyl-D-glucosamine (2-acetamido-2-deoxy-D-glucose); N-acetyl-D-galactosamine (2-acetamido-2-deoxy-r> galactose); and sialic acid. Sialic acid is the general name given to any substituted neuraminic acid. In humans the only important sialic acid is//-acetylneuraminic acid (5-acetamido-3, 5-