Enhancing attention and memory of individuals at clinical high risk for psychosis with mHealth technology
Enhancing attention and memory of individuals at clinical high risk for psychosis with mHealth technology
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DOI：
10.1016/j.ajp.2021.102587
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发表时间：
2021-02-19
影响因子：
9.5
通讯作者：
Wang, Jijun
中科院分区：
文献类型：
--
作者：
Li, Huijun;Yang, Shuwen;Wang, Jijun
背景：认知障碍对临床精神病高危人群的社会和角色功能有不良影响，已成为干预的重要对象。移动健康应用具有用户友好、实时、个性化、便携等特点，在心理健康领域具有广阔的应用前景。方法：80例CHR患者随机分为干预组和对照组。干预组的CHR受试者通过智能手机上的特定记忆注意资源和训练（SMART）应用程序进行注意和记忆训练，每天10分钟，每周5天，持续3个月。两组均随访3个月。在基线和随访阶段，使用matrix共识认知电池（MCCB）测量认知功能。在随访中，干预组完成移动应用评定量表（Mobile Application Rating Scale， MARS），提供反馈以改善SMART。结果：在3个月的随访中，干预组在注意/警觉性领域存在显著的时间交互效应，且干预组显著优于对照组。干预组注意力/警觉性的改善与认知训练时间的长短有显著关系。总体功能评估（GAF）基线降低率可以预测注意力/警觉性的改善。MARS结果表明，CHR受试者接受SMART。结论：移动技术可以改善CHR患者的认知功能，尤其是注意/警觉领域。
Background: Cognitive impairment has adverse impact on the social and role functions of those at clinical high risk for psychosis and it has become an important target for intervention. Mobile health applications are userfriendly, real-time, personalized and portable in administering cognitive training and have promising application prospects in the field of mental health.Methods: Eighty CHR subjects were randomized into an intervention group and a control group. CHR subjects of the intervention group performed attention and memory training via a Specific Memory Attention Resource and Training (SMART) application in their smart phones for 10 min per day, five days per week for three months. Both groups were followed up for three months. At baseline and follow-up phases, cognitive function was measured using the MATRICS Consensus Cognitive Battery (MCCB). In the follow-up, the intervention group completed the Mobile Application Rating Scale (MARS) to provide feedback to improve SMART.Results: There is a significant group by time interaction effect in the Attention/Vigilance domain, which is significantly better in the intervention group than in the control group at 3- month follow-up. The improvement in Attention/Vigilance in the intervention group is significantly related to the amount of cognitive training time. Global Assessment of Function (GAF) reduction rate at baseline could predict the improvement of Attention/ Vigilance. MARS results indicate that CHR subjects were receptive of SMART.Conclusion: Mobile technology can be applied to improve cognitive function of CHR individuals, especially in the Attention/Vigilance domain.