Fetal thymic involution: A sonographic marker of the fetal inflammatory response syndrome

Fetal thymic involution: A sonographic marker of the fetal inflammatory response syndrome
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DOI:
10.1016/j.ajog.2005.05.036
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发表时间:
2006-01-01
影响因子:
9.8
通讯作者:
Loverro, G
Loverro, G
中科院分区:
医学1区
文献类型:
--
作者:
Di Naro, E;Cromi, A;Loverro, G

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目的:探讨超声检查胎儿胸腺大小与早产患者宫内感染的关系。研究设计:31例早产且胎膜完整的孕妇,孕24~32周。超声测量胎儿胸腺周长,羊膜穿刺术进行羊膜腔微生物检查。结果:早产的发生率为51.6%(16/31),羊水内感染的发生率为32.3%(10/31)。宫内感染组和非宫内感染组胎儿胸腺周长均低于胎龄第5百分位数(10/10例比5/21例;P
Objective: The purpose of this study was to evaluate whether there is a relationship between the sonographic fetal thymus size and the presence of an intrauterine infection in patients with preterm labor.Study design: Thirty-one women who had been admitted with preterm labor and intact membra ties between 24 and 32 weeks of gestation were included. Fetal thymus perimeter was measured sonographically, and amniocentesis for the microbiologic assessment of the amniotic cavity was performed. Placentas and umbilical cords were examined for the presence of chorioamnionitis/funisitis.Results: The prevalence of preterm delivery and intra-amniotic infection was 51.6% (16/31 women) and 32.3% (10/31 women), respectively. In all cases with intrauterine infection and in 23.81% of cases without intrauterine infection, the fetal thymus perimeter was below the 5th percentile for gestational age (10/10 women vs 5/21 women; P