Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver
Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver
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DOI：
10.1038/ajg.2016.318
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发表时间：
2017-01-01
影响因子：
9.8
通讯作者：
Aigner, Elmar
中科院分区：
文献类型：
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作者：
Feldman, Alexandra;Eder, Sebastian K.;Aigner, Elmar
目的：非酒精性脂肪性肝病（NAFLD）与肥胖密切相关；然而，5-8%的瘦人也有NAFLD的证据。我们的目的是研究消瘦高加索NAFLD患者的临床、遗传、代谢和生活方式特征。方法：选取187名受试者，根据体重指数（BMI）和肝脏脂肪变性超声检查结果分为三组
OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is closely linked to obesity; however, 5-8% of lean subjects also have evidence of NAFLD. We aimed to investigate clinical, genetic, metabolic and lifestyle characteristics in lean Caucasian subjects with NAFLD.METHODS: Data from 187 subjects allocated to one of the three groups according to body mass index (BMI) and hepatic steatosis on ultrasound were obtained: lean healthy (BMI