Haemostatic and other risk factors for ischaemic heart disease and social class: evidence from the Caerphilly and Speedwell studies.
Haemostatic and other risk factors for ischaemic heart disease and social class: evidence from the Caerphilly and Speedwell studies.
复制标题
缺血性心脏病和社会阶层的止血和其他危险因素：来自卡菲利和斯皮德韦尔研究的证据。
DOI：
--
复制
发表时间：
1988
影响因子：
7.7
通讯作者：
P. C. Elwood
中科院分区：
文献类型：
--
作者：
I. A. Baker;P. Sweetnam;J. G. Yarnell;D. Bainton;P. C. Elwood
社会阶层与缺血性心脏病（IHD）的死亡率之间存在明显的关联。利用Caerphilly和Speedwell心脏病协作研究的数据，探讨了一些已知的IHD风险因素与社会阶层之间的关系。总的结论是，血脂和肥胖不太可能在解释缺血性心脏病的社会差异方面发挥任何作用。可能涉及血压，特别是收缩压，但两个数据集不一致，仅在Speedwell中显示了相关性。不同社会阶层的止血相关变量存在显著差异，Caerphilly和Speedwell的模式相似。因此，缺血性心脏病的分类模式可能至少部分是由止血机制的差异产生的。这些止血功能的差异几乎完全是由于吸烟习惯的巨大社会阶层差异。因此，IHD的阶级差异可能是由于吸烟习惯的差异。
There are marked associations between social class and mortality from ischaemic heart disease (IHD). Using data from the Caerphilly and Speedwell Collaborative Heart Disease Studies the relationships between a number of known risk factors for IHD and social class are explored. The overall conclusions are that lipids and obesity are unlikely to play any part in explaining social differences in ischaemic heart disease. Blood pressure, particularly stystolic pressure, could be involved but the two data sets are inconsistent and associations are only shown in Speedwell. There are marked differences in the haemostatic related variables in the various social classes and the pattern of these is similar in Caerphilly and Speedwell. It is possible therefore that the class pattern of IHD is generated, in part at least, by differences in haemostatic mechanisms. These differences in haemostatic function are almost entirely due to the large social class differences in smoking habit. It is possible therefore that the class differences in IHD result from differences in smoking habit.