Histomorphometric comparison between continuous and discontinuous distraction osteogenesis
Histomorphometric comparison between continuous and discontinuous distraction osteogenesis
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DOI：
10.1016/j.jcms.2009.03.006
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发表时间：
2009-10-01
影响因子：
3.1
通讯作者：
van der Wal, K. G. H.
中科院分区：
文献类型：
--
作者：
Djasim, U. M.;Mathot, B. J.;van der Wal, K. G. H.
Introduction: Experimental research on optimising the distraction protocol has been performed extensively in the past. However, relatively little research has been done on the rhythm of distraction. Findings in the orthopaedic literature showed that the outcome of distraction osteogenesis (DO) is positively influenced by increasing the rhythm of distraction. The aim of this study is to quantitatively compare continuous with discontinuous rhythms of distraction in rabbits. Materials and methods: Tissue blocks of regenerated bone were harvested from thirty-eight young adult female New-Zealand White rabbits. After a latency period of three days, rabbits were subjected for eleven days to either single daily activation of the distractor at a rate of 0.9 mm/d, or triple daily activation at a rate of 0.9 mm/d, or continuous activation at a rate of 0.9 mm/d. After three weeks of consolidation, bone regenerates were analysed using histomorphometry. Results: The continuous DO group showed significantly (p
