Mobile introns and intron-encoded proteins.
Mobile introns and intron-encoded proteins.
复制标题
移动内含子和内含子编码的蛋白质。
DOI:
10.1126/science.2479980
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发表时间:
1989
期刊:
影响因子:
--
通讯作者:
Butow,RA
中科院分区:
文献类型:
--
作者:
Perlman,PS;Butow,RA
T IS GENERALLY BELIEVED THAT SPLIT GENES IN THE NUCLEAR genomes of eukaryotes arose by a process ofexon shuffling (1). Once formed, the intervening sequences would be free to evolve in the absence of direct selection pressures to forms no longer recognizable (or barely so) from their progenitors. In this perspec-tive, we review and discuss some implications of recent findings of directed insertion of a class of related intron elements. These new data raise the likelihood that intron mobility was another source of split genes.