The Focal Adhesion Analysis Server: a web tool for analyzing focal adhesion dynamics.
The Focal Adhesion Analysis Server: a web tool for analyzing focal adhesion dynamics.
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DOI：
10.12688/f1000research.2-68.v1
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Gomez SM
中科院分区：
文献类型：
--
作者：
Berginski ME;Gomez SM
粘着斑分析服务器 (FAAS) 是一组计算机视觉算法的基于网络的实现，旨在量化二维培养物中成像的细胞中粘着斑的行为。输入由标记的粘着斑蛋白的一幅或多幅图像组成。系统的输出包括对每个图像中存在的粘附力的一系列静态和动态测量，以及这些属性如何随时间变化。用户能够调整几个对于正确的粘着斑识别很重要的参数。该系统为光学显微镜研究中常见的粘着斑行为的全局、公正评估提供了一个简单的工具。网络服务器位于：http://faas.bme.unc.edu/。
The Focal Adhesion Analysis Server (FAAS) is a web-based implementation of a set of computer vision algorithms designed to quantify the behavior of focal adhesions in cells imaged in 2D cultures. The input consists of one or more images of a labeled focal adhesion protein. The outputs of the system include a range of static and dynamic measurements for the adhesions present in each image as well as how these properties change over time. The user is able to adjust several parameters important for proper focal adhesion identification. This system provides a straightforward tool for the global, unbiased assessment of focal adhesion behavior common in optical microscopy studies. The webserver is available at: http://faas.bme.unc.edu/.