The Autism Diagnostic Observation Schedule, Toddler Module: Standardized Severity Scores
The Autism Diagnostic Observation Schedule, Toddler Module: Standardized Severity Scores
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DOI：
10.1007/s10803-015-2432-7
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发表时间：
2015-09-01
影响因子：
3.9
通讯作者：
Lord, Catherine
中科院分区：
文献类型：
--
作者：
Esler, Amy N.;Bal, Vanessa Hus;Lord, Catherine
针对自闭症诊断观察量表第二版（ADOS - 2）模块1 - 4，已创建了标准化校准严重程度评分（CSS），作为自闭症特定行为相对严重程度的衡量指标。为幼儿模块创建了总体和领域CSS，以便于与其他模块进行比较。分析包括388名12 - 30个月的自闭症儿童，并对127名自闭症儿童的435次重复评估进行了重复分析。与原始分数相比，在原始样本中总体和领域CSS与参与者特征之间的关联有所减少。在重复样本中，言语智商对社交影响 - CSS的影响并未减少。幼儿模块CSS提高了ADOS - 2各模块分数的可比性，并使症状发展轨迹的研究能够延伸到更年幼的年龄。
Standardized calibrated severity scores (CSS) have been created for Autism Diagnostic Observation Schedule, 2nd edition (ADOS-2) Modules 1-4 as a metric of the relative severity of autism-specific behaviors. Total and domain CSS were created for the Toddler Module to facilitate comparison to other modules. Analyses included 388 children with ASD age 12-30 months and were replicated on 435 repeated assessments from 127 children with ASD. Compared to raw scores, associations between total and domain CSS and participant characteristics were reduced in the original sample. Verbal IQ effects on Social Affect-CSS were not reduced in the replication sample. Toddler Module CSS increases comparability of ADOS-2 scores across modules and allows studies of symptom trajectories to extend to earlier ages.