Methods for Estimation of Statistical Properties of Envelopes of Ultrasonic Echoes from Myocardium
Methods for Estimation of Statistical Properties of Envelopes of Ultrasonic Echoes from Myocardium
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DOI：
10.1109/tmi.1987.4307844
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发表时间：
1987
影响因子：
10.6
通讯作者：
K. Wear;R. Popp
中科院分区：
文献类型：
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作者：
K. Wear;R. Popp
一些研究人员已经从心肌超声回波包络的统计特性中描述了各种形式的心脏病。特别地，包络概率密度函数的平均标准差比（MSR）、偏度和峰度已被用于检测心肌缺血、梗死、再灌注和肥大。在本文中，组织声学特性以外的现象对统计参数估计的影响进行了研究。这些包括系统特性（中心频率、带宽、波束宽度等），样本体积尺寸和组织速度。在心肌中，相对少量的组织可用于询问。结果表明，在这些有限的数据采集条件下，可能会发生大量的统计参数的估计系统偏差。推导了包络方差估计误差的解析形式。估计的包络平均值，方差，MSR，偏度和峰度的实验研究，使用商业医疗超声扫描仪和仿组织体模。
Several investigators have characterized various forms of heart disease from the statistical properties of envelopes of ultrasonic echos from myocardium. In particular, the mean-to-standard deviation ratio (MSR), skewness, and kurtosis of the envelope probability density function have been used for the detection of myocardial ischemia, infarction, reperfusion, and hypertrophy. In this paper, the effects of phenomena other than tissue acoustic properties upon estimates of statistical parameters are investigated. These include system characteristics (center frequency, bandwidth, beam width, etc.), sample volume dimensions, and tissue velocity. In myocardium, relatively small amounts of tissue are available for interrogation. It is shown that, under these limited data acquisition conditions, substantial systematic biases in the estimates of statistical parameters may occur. Analytic forms for errors in the envelope variance estimate are derived. Estimation of the envelope mean, variance, MSR, skewness, and kurtosis is investigated experimentally, using a commercial medical ultrasound scanner and a tissue-mimicking phantom.