A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae)

A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae)
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DOI:
10.1080/14786419.2017.1315720
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发表时间:
2017-04
影响因子:
2.2
通讯作者:
Y. M. Mba Nguekeu;M. Awouafack;P. Tane;Marius Roch Nguedia Lando;T. Kodama;H. Morita
Y. M. Mba Nguekeu;M. Awouafack;P. Tane;Marius Roch Nguedia Lando;T. Kodama;H. Morita
中科院分区:
化学3区
文献类型:
--
作者:
Y. M. Mba Nguekeu;M. Awouafack;P. Tane;Marius Roch Nguedia Lando;T. Kodama;H. Morita

文献摘要

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从山毛豆枝叶的甲醇提取物中分离得到一个新的山柰酚三糖苷,命名为山毛豆苷(1),以及五个已知化合物:山毛豆素(2)、桦木酸(3)、羽扇豆醇(4)、β-谷甾醇(5)和β-谷甾醇的3-O-β-d-吡喃葡萄糖苷(6)。新化合物的结构通过NMR(1D和2D)和MS数据分析以及化学转化来表征。山毛豆苷(1)对肺炎克雷伯菌有较弱的抗菌活性,MIC值为150 μg/mL。
Abstract A phytochemical investigation of the MeOH extract of twigs and leaves of Tephrosia preussi was carried out to give a new kaempferol triglycoside, named tephrokaempferoside (1), together with five known compounds: tephrosin (2), betulinic acid (3), lupeol (4), β-sitosterol (5) and 3-O-β-d-glucopyranoside of β-sitosterol (6). The structure of the new compound was characterised by analyses of NMR (1D and 2D) and MS data, and chemical conversion. Tephrokaempferoside (1) had weak antibacterial activity against Klebsiella pneumoniae with an MIC value of 150 μg/mL.