Ameloblastomas:: a regional Latin-American multicentric study
Ameloblastomas:: a regional Latin-American multicentric study
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DOI：
10.1111/j.1601-0825.2006.01284.x
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发表时间：
2007-05-01
期刊：
影响因子：
3.8
通讯作者：
Meneses-Garcia, A.
中科院分区：
文献类型：
--
作者：
Ledesma-Montes, C.;Mosqueda-Taylor, A.;Meneses-Garcia, A.
目的：根据2005年WHO新的牙源性肿瘤分类标准对163例成釉细胞瘤进行分类，并对其临床和显微特征进行分析。方法：对来自墨西哥和危地马拉的9个拉美地区机构的163例成釉细胞瘤的临床病理特征进行分析。实体性成釉细胞瘤(SA)和单囊性成釉细胞瘤(UA)的平均年龄分别为41.4岁和26.3岁(P<；0.001)，男女受累几乎相同。UA和SA主要累及下颌骨。SA和UA的平均大小分别为6.2 cm和6.3 cm。复发率SA组为21.7%，UA组为12.6%。结论：在这项研究中，UA经常被误诊为SA；然而，有足够的临床和显微镜特征可以对这两种类型的成釉细胞瘤进行准确的鉴别，这应该被外科和预后所识别。在本研究中，在20岁以下的患者中未发现SA，UA有恒定的粘液间质，而成熟结缔组织更常与实质型相关。
Aim: To classify 163 ameloblastoma cases according to the new WHO Classification of Odontogenic Tumours (2005) and analyse their clinical and microscopic features.Methods: We studied the clinico-pathological features of 163 ameloblastoma cases from nine regional Latin-American institutions from Mexico and Guatemala.Results: Ameloblastomas comprised 22.7% of all odontogenic tumours. The mean age was 41.4 years for solid ameloblastoma (SA) and 26.3 years for unicystic ameloblastoma (UA) (P < 0.001) and both sexes were almost equally affected. The mandible was mainly affected for both UA and SA. The mean size was 6.2 cm for SA and 6.3 cm for UA cases. The recurrence rate was 21.7% for SA and 12.6% for UA. UA was twice as more frequent than the solid variant.Conclusions: In this study we found that UA was frequently misdiagnosed as SA; however, there are enough clinical and microscopic features that allow for an accurate differentiation between both types of ameloblastoma that should be recognized for surgical and prognostic purposes. In this study, SA was not found in patients younger than 20 years, UA had a constant myxoid stroma while mature connective tissue was more frequently associated with the solid type.