The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000
The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000
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DOI：
10.1093/nar/28.1.45
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发表时间：
2000-01-01
影响因子：
14.9
通讯作者：
Apweiler, R
中科院分区：
文献类型：
--
作者：
Bairoch, A;Apweiler, R
SWISS-PROT是一个精心策划的蛋白质序列数据库，致力于提供高水平的注释（如蛋白质功能的描述，其结构域结构，翻译后修饰，变体等），最低程度的冗余和与其他数据库的高度集成，数据库的最新发展包括格式和内容的增强，交叉引用其他数据库，新的文件档案和改进：TrEMBL，SWISS-PROT的计算机注释补充。TrEMBL由来自EMBL核苷酸序列数据库中所有编码序列（CDS）翻译的SWISS-PROT样格式的条目组成，除了SWISS-PROT中已经包含的CDS。我们还描述了人类蛋白质组学计划（HPI），这是一个根据SWISS-PROT的质量标准注释所有已知人类序列的主要项目，SWISS-PROT可在http://www.expasy.ch/sprot/和http://www.ebi.ac.uk/swissprot/上获得。
SWISS-PROT is a curated protein sequence database which:strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases, Recent developments of the database include format and content enhancements, cross-references to additional databases, new documentation files and improvements:to TrEMBL, a computer-annotated supplement to SWISS-PROT. TrEMBL consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDSs) in the EMBL Nucleotide Sequence Database, except the CDSs already included in SWISS-PROT. We also describe the Human Proteomics Initiative (HPI), a major project to annotate all known human sequences according to the quality standards of SWISS-PROT, SWISS-PROT is available at: http://www.expasy.ch/sprot/ and http://www.ebi.ac.uk/swissprot/.