Factors associated with postsurgical muscle weakness in patients who undergo thoracic aortic surgery: a retrospective cohort study

Factors associated with postsurgical muscle weakness in patients who undergo thoracic aortic surgery: a retrospective cohort study
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胸主动脉手术患者术后肌无力的相关因素:一项回顾性队列研究

DOI:
10.1080/09593985.2022.2068168
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发表时间:
2022
影响因子:
2
通讯作者:
Yamada S
Yamada S
中科院分区:
医学4区
文献类型:
--
作者:
Shimizu M;Adachi T;Kobayashi K;Mutsuga M;Oshima H;Usui A;Yamada S

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目的主动脉手术常用于老年患者,这些患者术后肌肉无力的风险较高。为了加强有目的的术后康复,我们旨在研究胸主动脉手术患者术后肌肉无力的相关因素。方法回顾性队列研究分析了2012年1月至2018年12月在大学医院连续行择期胸主动脉手术合并体外循环的患者的数据,这些患者术前和术后均测量了膝关节伸肌等长肌力(KEIS)。主要结局指标为KEIS变化百分比(% change in KEIS)。采用多元线性回归分析确定影响KEIS变化百分比的独立危险因素。结果共纳入218例患者。多元线性回归分析显示,机械通气时间、从最初坐着到100米行走的天数以及在康复室的运动次数与KEIS的%变化相关。结论本研究可为术后肌无力风险患者分层提供参考。胸主动脉手术患者的预防或替代干预措施将在未来的研究中进行评估。
ObjectiveAortic surgery is often performed in elderly patients, and these patients have a high risk of postsurgical muscle weakness. To reinforce purposeful postsurgical rehabilitation, we aimed to investigate the factors associated with postsurgical muscle weakness in patients who underwent thoracic aortic surgery.MethodsThis retrospective cohort study analyzed data of consecutive patients who underwent elective thoracic aortic surgery with cardiopulmonary bypass, and whose knee extensor isometric muscle strength (KEIS) were measured pre- and postoperatively at University Hospital between January 2012 and December 2018. The primary outcome was percent change in KEIS (% change in KEIS). Multivariate linear regression analysis was used to identify independent risk factors for % change in KEIS.ResultsOverall, 218 patients were included. Multivariate linear regression analysis showed that mechanical ventilation time, days from initial sitting to 100 m walking, and the number of exercises in the rehabilitation room were associated with % change in KEIS.ConclusionsThis study may serve as a reference to stratify patients at risk of postsurgical muscle weakness. The preventive or alternative interventions in patients undergoing thoracic aortic surgery will be assessed in future studies.
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