Characterization of bZip-Type Transcription Factor AtfA with Reference to Stress Responses of Conidia of Aspergillus nidulans
Characterization of bZip-Type Transcription Factor AtfA with Reference to Stress Responses of Conidia of Aspergillus nidulans
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DOI：
10.1271/bbb.80001
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发表时间：
2008-10-01
影响因子：
1.6
通讯作者：
Mizuno, Takeshi
中科院分区：
文献类型：
--
作者：
Hagiwara, Daisuke;Asano, Yoshihiro;Mizuno, Takeshi
在自然生境中生长的微生物永远面临着各种各样的外部压力。在真菌中，包括构巢曲霉（Aspergillus nidulans），在恶劣生境中生存的一般和最终策略之一是耐胁迫分生孢子的发育。在这项研究中，我们发现，碱性区域亮氨酸拉链转录因子之一，命名为AtfA，在收购对分生孢子的氧化和热胁迫的耐受性中起着至关重要的作用，但不是菌丝体，虽然这个因素本身并不参与无性发育。
Microorganisms growing in natural habitats are permanently confronted with a wide variety of external stresses. In fungi, including Aspergillus nidulans, one of the general and ultimate strategies to survive in harsh habitats is the development of stress-tolerant conidia. In this study, we found that one of the basic-region leucine zipper transcription factors, named AtfA, plays a crucial role in the acquisition of tolerance against oxidative and heat stress on conidia, but not on mycelia, although this factor is not involved in asexual development per se.