Psychosis risk screening in youth: A validation study of three self-report measures of attenuated psychosis symptoms

Psychosis risk screening in youth: A validation study of three self-report measures of attenuated psychosis symptoms
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DOI:
10.1016/j.schres.2012.07.022
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发表时间:
2012-10-01
影响因子:
4.5
通讯作者:
Schiffman, Jason
Schiffman, Jason
中科院分区:
医学2区
文献类型:
--
作者:
Kline, Emily;Wilson, Camille;Schiffman, Jason

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评估减弱的精神病症状的简短自我报告问卷有可能快速有效地筛查出许多可能从临床监测或早期干预中受益的人。当前的研究试图检查和比较减弱症状筛查工具与从临床医生实施的精神病风险综合征结构化访谈(SIPS)中获得的诊断的标准效度。在寻求心理健康服务的青少年和年轻成年人样本中,在SIPS访谈之前进行了三份筛查问卷(首要筛查问卷、前驱症状问卷 - 简版和青少年精神病风险问卷 - 简版)。使用问卷作者推荐的阈值以及根据经验得出的最佳阈值,获得了每种自我报告测量方法相对于SIPS诊断的敏感性、特异性、阳性预测值和总体准确性。筛查工具与SIPS高度相关,并在确定精神病风险状态方面表现出同等的总体效率。所有三种筛查工具似乎都是对减弱症状有用且有效的评估工具,每种工具都显示出相对优势。减弱症状筛查工具的验证是朝着能够早期、广泛地识别处于精神病病程中的个体迈出的重要一步。(C)2012爱思唯尔有限公司。保留所有权利。
Brief self-report questionnaires that assess attenuated psychosis symptoms have the potential to quickly and effectively screen many people who may benefit from clinical monitoring or early intervention. The current study sought to examine and compare the criterion validities of attenuated symptoms screening tools with diagnoses obtained from the clinician-administered Structured Interview for Psychosis Risk Syndromes (SIPS). Three screening questionnaires (Prime Screen, Prodromal Questionnaire-Brief, and Youth Psychosis At-Risk Questionnaire-Brief) were administered just prior to the SIPS interview in a sample of adolescents and young adults seeking mental health services. Using thresholds recommended by instrument authors as well as empirically derived optimal thresholds, the sensitivity, specificity, positive predictive value, and overall accuracy of each self-report measure with regard to SIPS diagnosis were obtained. Screeners correlated highly with the SIPS and demonstrated equivalent overall efficiency in capturing psychosis risk status. All three screeners appear to be useful and valid assessment tools for attenuated symptoms, with each instrument demonstrating relative benefits. The validation of attenuated symptoms screening tools is an important step toward enabling early, wide-reaching identification of individuals on a course toward psychotic illness. (C) 2012 Elsevier B.V. All rights reserved.