Pre- and Perinatal Risk Factors in Adults with Attention-Deficit/Hyperactivity Disorder
Pre- and Perinatal Risk Factors in Adults with Attention-Deficit/Hyperactivity Disorder
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DOI：
10.1016/j.biopsych.2011.11.013
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发表时间：
2012-03-01
影响因子：
10.6
通讯作者：
Haavik, Jan
中科院分区：
文献类型：
--
作者：
Halmoy, Anne;Klungsoyr, Kari;Haavik, Jan
Background: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent and disabling lifespan disorder, but little is yet known about risk factors for ADHD persisting beyond adolescence. The present study investigates the association between pregnancy and birth complications and ADHD in adulthood.Methods: We used data from the Medical Birth Registry of Norway to compare pre-and perinatal risk factors among 2323 adults approved for medical treatment for ADHD, with the remaining population born during the same years, 1967-1987, and surviving into adulthood (n = 1,170,073). Relative risks (RR) adjusted for potential confounders were calculated.Results: Preterm (< 37 weeks of gestation) and extremely preterm birth (< 28 weeks of gestation) were associated with 1.3- and 5-fold increased risks of ADHD, respectively. Birth weights
