Cognitive impairment in psychotic illness: prevalence, profile of impairment developmental course, and treatment considerations

Cognitive impairment in psychotic illness: prevalence, profile of impairment developmental course, and treatment considerations
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DOI:
10.31887/dcns.2019.21.3/amccleery
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发表时间:
2019-09-01
影响因子:
8.3
通讯作者:
Nuechterlein, Keith H.
Nuechterlein, Keith H.
中科院分区:
医学2区
文献类型:
--
作者:
McCleery, Amanda;Nuechterlein, Keith H.

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尽管对精神病症状(如幻觉、妄想)有有效的药物治疗,但精神病患者的功能结局往往令人失望。虽然它不包括在精神障碍的诊断标准中,但认知障碍是这一临床人群中社区功能的最强决定因素之一,因此它是干预的重要目标。在这篇综述中,我们讨论了关于精神疾病认知障碍的主要研究领域。所涉及的具体主题包括:(i)精神障碍中认知障碍的患病率;(ii)精神病患者认知障碍的特征和程度;(iii)认知障碍的发展过程;(iv)认知障碍的纵向稳定性;(5)改善精神病患者认知能力的治疗方法。(C) 2019, AICH -施维雅集团
Despite effective pharmacological treatments for psychotic symptoms (eg, hallucinations, delusions), functional outcomes for people with psychotic disorders are often disappointing. Although it is not included in the diagnostic criteria for psychotic disorders, cognitive impairment is one of the strongest determinants of community functioning in this clinical population, and thus it is an important target for intervention. In this review, we discuss the major areas of research regarding impaired cognition in psychotic illness. The specific topics covered include: (i) the prevalence of cognitive impairment in psychotic disorders; (ii) the profile and magnitude of cognitive impairment in psychotic disorders; (iii) the developmental course of cognitive impairment; (iv) the longitudinal stability of cognitive impairment; and (v) treatment approaches to improve cognitive performance in people with psychotic disorders. (C) 2019, AICH - Servier Group