Simultaneous determination of N-methylcarbamate pesticides by LC/atmospheric pressure-ionization MS.
Simultaneous determination of N-methylcarbamate pesticides by LC/atmospheric pressure-ionization MS.
复制标题
LC/大气压离子化质谱同时测定 N-甲基氨基甲酸酯类农药。
DOI：
10.2116/bunsekikagaku.46.555
复制
发表时间：
1997
期刊：
影响因子：
0.2
通讯作者：
S. Daishima
中科院分区：
文献类型：
--
作者：
M. Takino;Takashi Yamagami;S. Daishima
建立了n -甲基氨基甲酸酯类农药的液相色谱/质谱联用分析方法。在反相液相色谱条件下，采用常压化学电离（APCI）和电喷雾电离（ESI）方法对七种n -甲基氨基甲酸酯类农药进行了分析。考察了液相色谱流动相添加剂、ESI法毛细管出口电压和APCI法汽化器温度对n -甲基氨基甲酸酯检测灵敏度的影响。ESI方法的灵敏度高于APCI方法。将大量的河水样品直接注入前柱，然后利用柱切换技术将n-甲基氨基甲酸酯通过分析柱分离。这些农药的检出限为20 ~ 100毫微克。农药在河流水体中的总回收率为92 ~ 101%，RSD（n =5）为1.7 ~ 3.3%。
An analytical method for the determination of N-methylcarbamate pesticides with liquid chromatography/mass spectrometry (LC/MS) has been developed. Under reversed-phase liquid-chromatographic conditions seven N-methylcarbamate pesticides have been analyzed using atmospheric-pressure chemical ionization (APCI) and electrospray ionization (ESI) methods. The effects of additives to the liquid chromatographic mobile phase, the capillary exit voltage with ESI methods and the temperature of the vaporizer with APCI methods on the sensitivity for the detection of N-methylcarbamates were examined. The sensitivities of the ESI methods were higher than those of APCI methods. Large volumes of river-water samples were directly injected into the precolumn, and then N-methylcarbamates were separated by an analytical column with a column-switching technique. The detection limits of these pesticides ranged from 20 ppt to 100 ppt. The overall recoveries of pesticides were from 92 to 101 % {RSD(n =5) were from 1.7 to 3.3%} for river water.