Short-latency discriminative unit response: Engram or bias?
Short-latency discriminative unit response: Engram or bias?
复制标题
短延迟判别单元响应：印迹还是偏差？
DOI：
--
复制
发表时间：
1976
期刊：
影响因子：
--
通讯作者：
M. Gabriel
中科院分区：
文献类型：
--
作者：
M. Gabriel
最近的研究表明，在条件反射过程中，CS相关的神经元活动发生了变化。这些变化在性质上是关联的，类似于条件反射导致的行为变化。然而，与行为条件反应不同，神经元反应的潜伏期非常短(5-35毫秒)。本文检验了两种解释短潜伏期联想活动的假说。一种假设是在记录电极附近获得神经元修饰(印迹)。第二个假说假设来自遥远的神经轨迹的一股紧张性冲动流，它偏向于记录的神经元的活动，以产生联想反应。基于印记假设的某些不可信的含义，我们考察了每一种观点的含义，并断言了偏见假设的更大吸引力。最近获得的数据支持偏向假说，而不是印痕假说。
Recent studies have shown changes during conditioning in CS-related neuronal activity. The changes were associative in character, similar to behavioral changes which result from conditioning. However, unlike behavioral conditioned responses, the neuronal responses had very short latencies (5-35 msec). In the present paper, two hypotheses accounting for the short-latency associative activity are examined. One hypothesis assumes acquisition of a neuronal modification (engram) in the vicinity of the recording electrode. The second hypothesis postulates a tonic flow of impulses originating from a distant neural locus, which biases the activity of the recorded neurons to produce the associative response. Implications of each viewpoint are examined and the greater appeal of the bias hypothesis is asserted, based upon certain implausible implications of the engram hypothesis. Recently obtained data are presented which favor the bias hypothesis over the engram hypothesis for one CNS locality.