INTERMITTENT CLAUDICATION - FACTORS DETERMINING OUTCOME
INTERMITTENT CLAUDICATION - FACTORS DETERMINING OUTCOME
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DOI：
10.1136/bmj.1.6124.1377
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发表时间：
1978-01-01
影响因子：
--
通讯作者：
WALTON, I
中科院分区：
文献类型：
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作者：
HUGHSON, WG;MANN, JI;WALTON, I
两组患者在首次转诊或入院治疗间歇性跛行（IC）后随访4 - 8年，研究疾病的自然史和决定其结局的因素。在一个60例患者的系列研究中，那些在转诊后停止或减少吸烟的患者预后有很大改善。因此，即使在诊断为IC后，鼓励患者戒烟也是非常重要的，因为这个可纠正的因素在决定结果方面似乎比其他不太适合治疗的疾病的医学风险因素更重要。在第二项研究中，160名患者在首次入院后随访了8年。他们总共住院480次，住院11190天;他们60岁以后的预期寿命大约是一般人口的一半。年龄、冠状动脉疾病、脑血管疾病和糖尿病与不良结局相关。
Two groups of patients were followed up for four to eight years after first referral or admission to hospital for intermittent claudication (IC) in a study of the natural history of the disease and of factors determining its outcome. In one series of 60 patients, those who stopped or reduced smoking after referral had a much improved prognosis. Thus even after the diagnosis of IC it is extremely important that patients should be encouraged to stop smoking, since this correctable factor appears to be of greater importance in determining outcome than other medical risk factors for the disease that are less amenable to treatment. In the second study, 160 patients were followed up for eight years after first hospital admission. They had a total of 480 hospital admissions and had spent 11 190 days in hospital; their life expectancy after the age of 60 was about half that of the general population. Age, coronary artery disease, cerebrovascular disease, and diabetes were associated with an adverse outcome.