Dietary protein-to-carbohydrate ratio and added sugar as determinants of excessive gestational weight gain: a prospective cohort study.
Dietary protein-to-carbohydrate ratio and added sugar as determinants of excessive gestational weight gain: a prospective cohort study.
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DOI：
10.1136/bmjopen-2014-005839
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发表时间：
2015-02-10
期刊：
影响因子：
2.9
通讯作者：
Olsen SF
中科院分区：
文献类型：
--
作者：
Maslova E;Halldorsson TI;Astrup A;Olsen SF
探讨妊娠期蛋白质与碳水化合物（P/C）比值和糖摄入量与妊娠期体重增加（GWG）的关系。一个出生前队列，包括103119怀孕登记1996年至2003年。 丹麦的所有妇女，如果她们讲丹麦语，并计划进行足月妊娠，都有资格参加。孕妇在第一次产前访视（妊娠6-10周）期间被招募和登记。 参与者包括活产单胎的妇女和完整的饮食摄入量和GWG数据，留下46262名妇女进行分析。 大量营养素的摄入量进行了量化，使用验证的食物频率问卷管理在妊娠第25周。P/C比率和添加糖的摄入量在五分位数中进行了检查。GWG基于妊娠12周和30周的自我报告体重，并定义为以g/周为单位的增加。我们使用多变量线性回归，包括调整孕前体重指数，计算GWG的相对变化和95%CI。平均GWG为471（224）g/周。在P/C比的最高（Q5）与最低（Q1）五分位数中，调整后的体重增加量低16 g/周（95% CI 9至22，趋势p <0.001）（整个妊娠期间平均减少约3%）。蛋白质摄入量>20%E vs <12%E的体重增加量低36 g/周（95%CI 20 - 53，趋势p <0.0001;平均减少1.8%）。 高P/C比与添加糖的摄入量呈负相关。添加糖摄入量与GWG密切相关（Q5 vs Q1：34，95% CI 28 - 40 g/周，趋势p <0.0001）。 高P/C比与GWG减少相关。这种关联似乎部分是由添加糖摄入量的减少引起的。这些结果与在非妊娠受试者中进行的随机试验一致。针对增加P/C比率并强调减少添加糖的饮食干预有助于减少过量的GWG。
To examine the relation between the protein:carbohydrate (P/C) ratio and added sugar intake in pregnancy and gestational weight gain (GWG). A prebirth cohort including 103 119 pregnancies enrolled between 1996 and 2003. All women in Denmark were eligible to participate if they spoke Danish and were planning to carry to term.The pregnant women were recruited and enrolled during their first antenatal visit (6–10 weeks of gestation). Participants included women with live-born singletons and complete data on dietary intake and GWG, leaving 46 262 women for the analysis. Macronutrient intake was quantified using a validated food frequency questionnaire administered in the 25th week of gestation. The P/C ratio and added sugar intake were examined in quintiles. GWG was based on self-reported weight in gestational weeks 12 and 30 and defined as gain in g/week. We used multivariable linear regression, including adjusting for pre-pregnancy body mass index, to calculate relative change in GWG and 95% CI. Average GWG was 471(224) g/week. The adjusted weight gain was 16 g/week lower (95% CI 9 to 22, p for trend <0.001) in the highest (Q5) versus lowest (Q1) quintile of the P/C ratio (∼3% average reduction across the entire pregnancy). Weight gain for those with >20%E vs <12%E from protein was 36 g/week lower (95% CI 20 to 53, p for trend <0.0001; ∼8% average reduction). A high P/C ratio was inversely related to intake of added sugars. Added sugar consumption was strongly associated with GWG (Q5 vs Q1: 34, 95% CI 28 to 40 g/week, p for trend <0.0001). A high P/C ratio was associated with reduced GWG. This association appeared to be partly driven by a decrease in intake of added sugar. These results are consistent with randomised trials in non-pregnant participants. A dietary intervention targeting an increased P/C ratio with emphasis on reducing added sugar can contribute to reducing excessive GWG.
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影响因子：
11.4
作者：
Jeffries, Kirby;Shub, Alexis;Permezel, Michael
通讯作者：
Permezel, Michael
影响因子：
4.7
作者：
Kinnunen, T. I.;Pasanen, M.;Luoto, R.
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作者：
Cucó, G;Fernández-Ballart, J;Arija, V
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影响因子：
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作者：
Guelinckx, Isabelle;Devlieger, Roland;Vansant, Greet
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Vansant, Greet
DOI：
10.1016/0002-9378(95)90598-7
发表时间：
1995-02-01
影响因子：
9.8
作者：
COGSWELL, ME;SERDULA, MK;YIP, R
通讯作者：
YIP, R