The effect of Qat chewing on blood pressure and heart rate in healthy volunteers

The effect of Qat chewing on blood pressure and heart rate in healthy volunteers
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DOI:
10.1177/004947550003000219
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发表时间:
2000-04-01
期刊:
影响因子:
0.6
通讯作者:
Murray-Lyon, IM
Murray-Lyon, IM
中科院分区:
医学4区
文献类型:
--
作者:
Hassan, NAGM;Gunaid, AA;Murray-Lyon, IM

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卡塔尔植物(Catha edulis Forsk)的叶子。含有安非他命类化合物的Celastraceae)在也门和东非被广泛咀嚼,因为它们具有令人愉悦的兴奋剂特性。还有一些不希望的副作用,本文研究了80名健康志愿者对心率和血压的影响。在咀嚼新鲜卡特叶的3小时期间,收缩压和舒张压以及心率显著且进行性升高,并且在咀嚼停止1小时后水平未恢复到基线水平。需要进一步研究经常咀嚼卡特可能引起的心血管疾病。
The leaves of the Qat plant (Catha edulis Forsk., Celastraceae) which contain amphetamine like compounds are widely chewed in Yemen and East Africa for their pleasurable stimulant properties. There are also a number of unwanted side-effects and this paper studies the effect on heart rate and blood pressure in 80 healthy volunteers. During a 3-h period of chewing fresh Qat leaves there was a significant and progressive rise in systolic and diastolic blood pressure and heart rate, and levels had not returned to baseline 1 h after chewing had ceased. Further studies are needed on possible cardiovascular morbidity associated with regular Qat chewing.