Visual field defects in acute optic neuritis - distribution of different types of defect pattern, assessed with threshold-related supraliminal perimetry, ensuring high spatial resolution
Visual field defects in acute optic neuritis - distribution of different types of defect pattern, assessed with threshold-related supraliminal perimetry, ensuring high spatial resolution
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DOI：
10.1007/s00417-007-0722-2
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发表时间：
2008-04-01
影响因子：
2.7
通讯作者：
Schiefer, U.
中科院分区：
文献类型：
--
作者：
Nevalainen, J.;Krapp, E.;Schiefer, U.
目的 使用阈值相关的轻微超阈值视野检查，评估临床诊断为视神经炎 (ON) 的眼睛及其当前未受影响的对侧眼的视野缺损 (VFD) 模式和局部空间频率分布，确保高空间分辨率。 方法 使用 Tubingen 自动视野计（TAP，Oculus Inc.，Dudenhofen，德国）和 Octopus 101 视野计（Haag-Streit Inc.， Koeniz，瑞士）使用中央 30 度视野内 191 个静态目标的标准化网格进行回顾性分析。 VFD 被分为 15 个类别。 结果 对 99 名临床诊断为急性视神经炎的患者（26 名男性和 73 名女性受试者，年龄从 18 至 51 岁）（52 只右眼，48 只受影响的左眼，1 只双侧受累）的视野 (VF) 进行了评估。中央暗点是相关眼中最常见的发现，占受影响眼中所有 VFD 的 41%。在所有 VFD 中，29% 发现神经纤维束缺陷，14% 发现旁中央暗点。 65% 的临床单眼近视患者的双眼周边视力正常。 21%的对侧眼出现神经纤维束缺损，9%的对侧眼出现弥漫性暗点。结论 中央暗点和视网膜神经纤维束缺损是急性ON最常见的VFD。自动阈值视野检查及其相对粗糙的网格很可能会漏掉小的中央和旁中央暗点，而这些暗点可以通过阈值相关的、稍微超阈值的策略来检测。在临床上明显的单眼视神经炎的对侧眼中，35% 存在视野缺损。
Purpose To assess the pattern and the local spatial frequency distribution of visual field defects (VFDs) in eyes with clinically diagnosed optic neuritis (ON) and their currently unaffected fellow eyes, using threshold-related, slightly supraliminal perimetry, ensuring high spatial resolution.Methods Records obtained with the Tubingen Automatic perimeter (TAP, Oculus Inc., Dudenhofen, Germany) and the Octopus 101 perimeter (Haag-Streit Inc, Koeniz, Switzerland), using a standardized grid of 191 static targets within the central 30 degrees visual field, were analysed retrospectively. VFDs were assigned to 15 classes.Results Visual fields (VF) from 99 patients (26 male and 73 female subjects, aged from 18 to 51 years) with clinically diagnosed, acute ON (52 right eyes, 48 left eyes affected, one bilateral involvement) were evaluated. Central scotomas were the most common finding in associated eyes, covering 41% of all VFDs in affected eyes. Nerve fibre bundle defects were found in 29% and paracentral scotomas in 14% of all VFDs. Fellow eyes were perimetrically normal in 65% of the clinically monocular ONs. Nerve fibre bundle defects were found in 21% and diffuse scotomas in 9% of the fellow eyes.Conclusions Central scotomas and retinal nerve fibre bundle defects are the most common VFDs in acute ON. Small central and paracentral scotomas that most probably would have been missed by automated thresholding perimetry with its relatively coarse grid could be detected by threshold-related, slightly supraliminal strategy. Of the fellow eyes in clinically apparent monocular optic neuritis, 35% present with visual field defects.